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Synthesis of radiolabeled nicotinamide cofactors from labeled pyridines: versatile probes for enzyme kinetics
(14)C-labeled nicotinamide cofactors are widely employed in biomedical investigations, e.g. to delineate metabolic pathways, to elucidate enzymatic mechanisms, or as substrates in kinetic isotope effect (KIE) experiments. The (14)C-label has generally been located remote from the reactive position,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3472106/ https://ncbi.nlm.nih.gov/pubmed/22922383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.08.012 |
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