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Microscale synthesis and kinetic isotope effect analysis of (4R)-[Ad-(14)C, 4-(2)H] NADPH and (4R)-[Ad-(3)H,4-(2)H] NADPH
We present a one-pot chemo-enzymatic microscale synthesis of NADPH with two different patterns of isotopic labels: (4R)-[Ad-(14)C,4-(2)H] NADPH and (4R)-[Ad-(3)H,4-(2)H] NADPH. These co-factors are required by an enormous range of enzymes, and isotopically labeled nicotinamides are consequently of s...
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| Publicado no: | J Labelled Comp Radiopharm |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4452123/ https://ncbi.nlm.nih.gov/pubmed/26045633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.1660 |
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