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Isotope Effects as Probes for Enzyme Catalyzed Hydrogen-Transfer Reactions

Kinetic Isotope effects (KIEs) have long served as a probe for the mechanisms of both enzymatic and solution reactions. Here, we discuss various models for the physical sources of KIEs, how experimentalists can use those models to interpret their data, and how the focus of traditional models has gro...

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Publicat a:Molecules
Autors principals: Roston, Daniel, Islam, Zahidul, Kohen, Amnon
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342783/
https://ncbi.nlm.nih.gov/pubmed/23673528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18055543
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