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Isotope Effects as Probes for Enzyme Catalyzed Hydrogen-Transfer Reactions

Kinetic Isotope effects (KIEs) have long served as a probe for the mechanisms of both enzymatic and solution reactions. Here, we discuss various models for the physical sources of KIEs, how experimentalists can use those models to interpret their data, and how the focus of traditional models has gro...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Roston, Daniel, Islam, Zahidul, Kohen, Amnon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342783/
https://ncbi.nlm.nih.gov/pubmed/23673528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18055543
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