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Isotope Effects as Probes for Enzyme Catalyzed Hydrogen-Transfer Reactions

Kinetic Isotope effects (KIEs) have long served as a probe for the mechanisms of both enzymatic and solution reactions. Here, we discuss various models for the physical sources of KIEs, how experimentalists can use those models to interpret their data, and how the focus of traditional models has gro...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Roston, Daniel, Islam, Zahidul, Kohen, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342783/
https://ncbi.nlm.nih.gov/pubmed/23673528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules18055543
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