Cargando...
Nitric oxide produced endogenously is responsible for hypoxia-induced HIF-1α stabilization in colon carcinoma cells
Hypoxia-inducible factor-1 alpha (HIF-1α) is a critical regulator of cellular responses to hypoxia. Under normoxic conditions, cellular HIF-1α level is regulated by hydroxylation by prolyl hydroxylases (PHDs), ubiquitylation and proteasomal degradation. During hypoxia, degradation decreases and its...
Gardado en:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3472092/ https://ncbi.nlm.nih.gov/pubmed/22971010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300274a |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|