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Membrane-induced Lever Arm Expansion Allows Myosin VI to Walk with Large and Variable Step Sizes

Myosin VI, the only known minus-ended actin filament-dependent motor, plays diverse cellular roles both as a processive motor and as a mechanical anchor. Although myosin VI has a short lever arm containing only one “IQ-motif” and a unique insertion for CaM binding, the motor walks with large and var...

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Hlavní autoři: Yu, Cong, Lou, Jizhong, Wu, Jingjing, Pan, Lifeng, Feng, Wei, Zhang, Mingjie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471712/
https://ncbi.nlm.nih.gov/pubmed/22936804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.328781
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