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Role of the lever arm in the processive stepping of myosin V

Myosin V is a two-headed molecular motor that binds six light chains per heavy chain, which creates unusually long lever arms. This motor moves processively along its actin track in discrete 36-nm steps. Our model is that one head of the two-headed myosin V tightly binds to actin and swings its long...

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Autors principals: Purcell, Thomas J., Morris, Carl, Spudich, James A., Sweeney, H. Lee
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC137854/
https://ncbi.nlm.nih.gov/pubmed/12386339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182539599
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