Role of the lever arm in the processive stepping of myosin V

Myosin V is a two-headed molecular motor that binds six light chains per heavy chain, which creates unusually long lever arms. This motor moves processively along its actin track in discrete 36-nm steps. Our model is that one head of the two-headed myosin V tightly binds to actin and swings its long...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Purcell, Thomas J., Morris, Carl, Spudich, James A., Sweeney, H. Lee
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2002
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12386339/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.182539599
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