Myosin-V stepping kinetics: A molecular model for processivity

Myosin-V is a molecular motor that moves processively along its actin track. We have used a feedback-enhanced optical trap to examine the stepping kinetics of this movement. By analyzing the distribution of time periods separating discrete ≈36-nm mechanical steps, we characterize the number and dura...

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izdano v:	Proc Natl Acad Sci U S A
Principais autores:	Rief, Matthias, Rock, Ronald S., Mehta, Amit D., Mooseker, Mark S., Cheney, Richard E., Spudich, James A.
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 2000
Teme:	Biological Sciences
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10944217/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.17.9482
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