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Myosin-V stepping kinetics: A molecular model for processivity

Myosin-V is a molecular motor that moves processively along its actin track. We have used a feedback-enhanced optical trap to examine the stepping kinetics of this movement. By analyzing the distribution of time periods separating discrete ≈36-nm mechanical steps, we characterize the number and dura...

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Autors principals: Rief, Matthias, Rock, Ronald S., Mehta, Amit D., Mooseker, Mark S., Cheney, Richard E., Spudich, James A.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC16890/
https://ncbi.nlm.nih.gov/pubmed/10944217
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