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Membrane-induced Lever Arm Expansion Allows Myosin VI to Walk with Large and Variable Step Sizes
Myosin VI, the only known minus-ended actin filament-dependent motor, plays diverse cellular roles both as a processive motor and as a mechanical anchor. Although myosin VI has a short lever arm containing only one “IQ-motif” and a unique insertion for CaM binding, the motor walks with large and var...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471712/ https://ncbi.nlm.nih.gov/pubmed/22936804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.328781 |
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