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Processive steps in the reverse direction require uncoupling of the lead head lever arm of myosin VI

Myosin VI is the only known reverse-direction myosin motor. It has an unprecedented means of amplifying movements within the motor involving rearrangements of the converter subdomain at the C-terminus of the motor and an unusual lever arm projecting from the converter. While the average step size of...

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Detalhes bibliográficos
Main Authors: Ménétrey, Julie, Isabet, Tatiana, Ropars, Virginie, Mukherjea, Monalisa, Pylypenko, Olena, Liu, Xiaoyan, Perez, Javier, Vachette, Patrice, Sweeney, H. Lee, Houdusse, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472048/
https://ncbi.nlm.nih.gov/pubmed/22940248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.07.034
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