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Myosin VI Must Dimerize and Deploy Its Unusual Lever Arm in Order to Perform Its Cellular Roles
It is unclear if the reverse-direction myosin, myosin VI, functions as a monomer or dimer in cells and how it generates large movements on actin. We deleted a stable, single α-helix (SAH) domain that has been proposed to function as part of a lever arm to amplify movements, without impact on in vitr...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4476653/ https://ncbi.nlm.nih.gov/pubmed/25159143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.041 |
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