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Neogenin Interacts with Matriptase-2 to Facilitate Hemojuvelin Cleavage
Hemojuvelin (HJV) and matriptase-2 (MT2) are co-expressed in hepatocytes, and both are essential for systemic iron homeostasis. HJV is a glycosylphosphatidylinositol-linked membrane protein that acts as a co-receptor for bone morphogenetic proteins to induce hepcidin expression. MT2 regulates the le...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471701/ https://ncbi.nlm.nih.gov/pubmed/22893705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363937 |
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