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Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells
Hemojuvelin (HJV) was recently identified as a critical regulator of iron homeostasis. It is either associated with cell membranes through a glycosylphosphatidylinositol anchor or released as a soluble form. Membrane-anchored HJV acts as a coreceptor for bone morphogenetic proteins and activates the...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647676/ https://ncbi.nlm.nih.gov/pubmed/19029439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-174565 |
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