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Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells

Hemojuvelin (HJV) was recently identified as a critical regulator of iron homeostasis. It is either associated with cell membranes through a glycosylphosphatidylinositol anchor or released as a soluble form. Membrane-anchored HJV acts as a coreceptor for bone morphogenetic proteins and activates the...

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Bibliografiske detaljer
Main Authors: Maxson, Julia E., Enns, Caroline A., Zhang, An-Sheng
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647676/
https://ncbi.nlm.nih.gov/pubmed/19029439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-08-174565
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