PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity

Treatment-related toxicity can be life-threatening and is the primary cause of interruption or discontinuation of chemotherapy for acute lymphoblastic leukemia (ALL), leading to an increased risk of relapse. Mercaptopurine is an essential component of continuation therapy in all ALL treatment protoc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stocco, Gabriele, Yang, Wenjian, Crews, Kristine R., Thierfelder, William E., Decorti, Giuliana, Londero, Margherita, Franca, Raffaella, Rabusin, Marco, Valsecchi, Maria Grazia, Pei, Deqing, Cheng, Cheng, Paugh, Steven W., Ramsey, Laura B., Diouf, Barthelemy, McCorkle, Joseph Robert, Jones, Terreia S., Pui, Ching-Hon, Relling, Mary V., Evans, William E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2012
Pynciau:
Association Studies Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471396/
https://ncbi.nlm.nih.gov/pubmed/22846425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds302
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