Comprehensive predictions of target proteins based on protein-chemical interaction using virtual screening and experimental verifications

BACKGROUND: Identification of the target proteins of bioactive compounds is critical for elucidating the mode of action; however, target identification has been difficult in general, mostly due to the low sensitivity of detection using affinity chromatography followed by CBB staining and MS/MS analy...

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Detalhes bibliográficos
Main Authors: Kobayashi, Hiroki, Harada, Hiroko, Nakamura, Masaomi, Futamura, Yushi, Ito, Akihiro, Yoshida, Minoru, Iemura, Shun-ichiro, Shin-ya, Kazuo, Doi, Takayuki, Takahashi, Takashi, Natsume, Tohru, Imoto, Masaya, Sakakibara, Yasubumi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471015/
https://ncbi.nlm.nih.gov/pubmed/22480302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-12-2
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