Integrating Statistical Predictions and Experimental Verifications for Enhancing Protein-Chemical Interaction Predictions in Virtual Screening

Predictions of interactions between target proteins and potential leads are of great benefit in the drug discovery process. We present a comprehensively applicable statistical prediction method for interactions between any proteins and chemical compounds, which requires only protein sequence data an...

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Bibliografiske detaljer
Main Authors: Nagamine, Nobuyoshi, Shirakawa, Takayuki, Minato, Yusuke, Torii, Kentaro, Kobayashi, Hiroki, Imoto, Masaya, Sakakibara, Yasubumi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685987/
https://ncbi.nlm.nih.gov/pubmed/19503826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000397
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