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IQGAP1 Protein Regulates Nuclear Localization of β-Catenin via Importin-β5 Protein in Wnt Signaling

In the canonical Wnt signaling pathway, the translocation of β-catenin is important for the activation of target genes in the nucleus. However, the molecular mechanisms underlying its nuclear localization remain unclear. In the present study, we found IQGAP1 to be a regulator of β-catenin function v...

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Bibliografiset tiedot
Päätekijät: Goto, Toshiyasu, Sato, Atsushi, Adachi, Shungo, Iemura, Shun-ichiro, Natsume, Tohru, Shibuya, Hiroshi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868749/
https://ncbi.nlm.nih.gov/pubmed/24196961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.520528
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