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An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancer
In the absence of HER2 overexpression, triple-negative breast cancers (TNBCs) rely on signaling by epidermal growth factor receptor (EGFR/ErbB1/HER1) to convey growth signals and stimulate cell proliferation. Soluble EGF-like ligands are derived from their transmembrane precursors by ADAM proteases,...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3470813/ https://ncbi.nlm.nih.gov/pubmed/22926263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2220-4 |
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