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Phenotypic Diversity of Breast Cancer-Related Mutations in Metalloproteinase-Disintegrin ADAM12

Six different somatic missense mutations in the human ADAM12 gene have been identified so far in breast cancer. Five of these mutations involve highly conserved residues in the extracellular domain of the transmembrane ADAM12-L protein. Two of these extracellular mutations, D301H and G479E, have bee...

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Détails bibliographiques
Auteurs principaux: Qi, Yue, Duhachek-Muggy, Sara, Li, Hui, Zolkiewska, Anna
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961381/
https://ncbi.nlm.nih.gov/pubmed/24651654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092536
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