The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis

Clear cell-type renal cell carcinomas (clear RCC) are characterized almost universally by loss of heterozygosity on chromosome 3p, which usually involves any combination of three regions: 3p25-p26 (harboring the VHL gene), 3p12-p14.2 (containing the FHIT gene), and 3p21-p22, implying inactivation of...

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Main Authors: Dreijerink, Koen, Braga, Eleonora, Kuzmin, Igor, Geil, Laura, Duh, Fuh-Mei, Angeloni, Debora, Zbar, Berton, Lerman, Michael I., Stanbridge, Eric J., Minna, John D., Protopopov, Alexei, Li, Jingfeng, Kashuba, Vladimir, Klein, George, Zabarovsky, Eugene R.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC34698/
https://ncbi.nlm.nih.gov/pubmed/11390984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131216298
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