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Inactivation of RASSF1A, the tumor suppressor gene at 3p21.3 in extrahepatic cholangiocarcinoma

AIM: To evaluate the genetic and epigenetic inactivation mechanism of the RASSF1A tumor suppressor gene at 3p21.3 in extrahepatic cholangiocarcinoma. METHODS: RT-PCR was used to investigate the transcriptional expressing and re-expression of RASSF1A. RASSF1A mutation was analyzed with SSCP and selec...

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Publicado en:World J Gastroenterol
Main Authors: Chen, Yong-Jun, Tang, Qi-Bin, Zou, Shen-Quan
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250680/
https://ncbi.nlm.nih.gov/pubmed/15761971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i9.1333
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