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Silencing of RASSF3 by DNA Hypermethylation Is Associated with Tumorigenesis in Somatotroph Adenomas

The pathogenic mechanisms underlying pituitary somatotroph adenoma formation, progression are poorly understood. To identify candidate tumor suppressor genes involved in pituitary somatotroph adenoma tumorigenesis, we used HG18 CpG plus Promoter Microarray in 27 human somatotroph adenomas and 4 norm...

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Detalhes bibliográficos
Main Authors: Peng, Hu, Liu, Huanhai, Zhao, Shuwei, Wu, Jian, Fan, Jingping, Liao, Jianchun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610897/
https://ncbi.nlm.nih.gov/pubmed/23555615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059024
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