Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis

Hyperammonemia and sarcopenia (loss of skeletal muscle) are consistent abnormalities in cirrhosis and portosystemic shunting. We have shown that muscle ubiquitin-proteasome components are not increased with hyperammonemia despite sarcopenia. This suggests that an alternative mechanism of proteolysis...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Qiu, Jia, Tsien, Cynthia, Thapalaya, Samjhana, Narayanan, Arvind, Weihl, Conrad Chris, Ching, James K., Eghtesad, Bijan, Singh, Kamini, Fu, Xiaoming, Dubyak, George, McDonald, Christine, Almasan, Alex, Hazen, Stanley L., Naga Prasad, Sathyamangla V., Dasarathy, Srinivasan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469607/
https://ncbi.nlm.nih.gov/pubmed/22895779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00183.2012
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi