A Novel Role of IGF1 in Apo2L/TRAIL-Mediated Apoptosis of Ewing Tumor Cells

Insulin-like growth factor 1 (IGF1) reputedly opposes chemotoxicity in Ewing sarcoma family of tumor (ESFT) cells. However, the effect of IGF1 on apoptosis induced by apoptosis ligand 2 (Apo2L)/tumor necrosis factor (TNF-) related apoptosis-inducing ligand (TRAIL) remains to be established. We find...

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Detalhes bibliográficos
Main Authors: van Valen, Frans, Harrer, Henning, Hotfilder, Marc, Dirksen, Uta, Pap, Thomas, Gosheger, George, Humpf, Hans-Ulrich, Jürgens, Heribert
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469244/
https://ncbi.nlm.nih.gov/pubmed/23091403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/782970
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