The Receptor Tyrosine Kinase RON and Its Isoforms as Therapeutic Targets in Ewing Sarcoma

The receptor tyrosine kinase (RTK) RON is linked to an aggressive metastatic phenotype of carcinomas. While gaining interest as a therapeutic target, RON remains unstudied in sarcomas. In Ewing sarcoma, we identified RON among RTKs conferring resistance to insulin-like growth factor-1 receptor (IGF1...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Berning, Philipp, Hennemann, Carolin, Tulotta, Claudia, Schaefer, Christiane, Lechtape, Birgit, Hotfilder, Marc, El Gourari, Yassmine, Jürgens, Heribert, Snaar-Jagalska, Ewa, Hempel, Georg, Dirksen, Uta, Potratz, Jenny
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226494/
https://ncbi.nlm.nih.gov/pubmed/32272784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040904
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