The Receptor Tyrosine Kinase RON and Its Isoforms as Therapeutic Targets in Ewing Sarcoma

The receptor tyrosine kinase (RTK) RON is linked to an aggressive metastatic phenotype of carcinomas. While gaining interest as a therapeutic target, RON remains unstudied in sarcomas. In Ewing sarcoma, we identified RON among RTKs conferring resistance to insulin-like growth factor-1 receptor (IGF1...

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Опубликовано в: :Cancers (Basel)
Главные авторы: Berning, Philipp, Hennemann, Carolin, Tulotta, Claudia, Schaefer, Christiane, Lechtape, Birgit, Hotfilder, Marc, El Gourari, Yassmine, Jürgens, Heribert, Snaar-Jagalska, Ewa, Hempel, Georg, Dirksen, Uta, Potratz, Jenny
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226494/
https://ncbi.nlm.nih.gov/pubmed/32272784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040904
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