DNA damage response by single-strand breaks in terminally differentiated muscle cells and the control of muscle integrity

DNA single-strand breaks (SSB) formation coordinates the myogenic program, and defects in SSB repair in post-mitotic cells have been associated with human diseases. However, the DNA damage response by SSB in terminally differentiated cells has not been explored yet. Here we show that mouse post-mito...

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Hlavní autoři: Fortini, P, Ferretti, C, Pascucci, B, Narciso, L, Pajalunga, D, Puggioni, E M R, Castino, R, Isidoro, C, Crescenzi, M, Dogliotti, E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469061/
https://ncbi.nlm.nih.gov/pubmed/22705848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.53
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