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Terminally differentiated muscle cells are defective in base excision DNA repair and hypersensitive to oxygen injury
The differentiation of skeletal myoblasts is characterized by permanent withdrawal from the cell cycle and fusion into multinucleated myotubes. Muscle cell survival is critically dependent on the ability of cells to respond to oxidative stress. Base excision repair (BER) is the main repair mechanism...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2007
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040456/ https://ncbi.nlm.nih.gov/pubmed/17940040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701743104 |
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