Mcl-1 and Bcl-xL regulate Bak/Bax-dependent apoptosis of the megakaryocytic lineage at multistages

Anti-apoptotic Bcl-2 family proteins, which inhibit the mitochondrial pathway of apoptosis, are involved in the survival of various hematopoietic lineages and are often dysregulated in hematopoietic malignancies. However, their involvement in the megakaryocytic lineage is not well understood. In the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kodama, T, Hikita, H, Kawaguchi, T, Shigekawa, M, Shimizu, S, Hayashi, Y, Li, W, Miyagi, T, Hosui, A, Tatsumi, T, Kanto, T, Hiramatsu, N, Kiyomizu, K, Tadokoro, S, Tomiyama, Y, Hayashi, N, Takehara, T
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Original Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469054/
https://ncbi.nlm.nih.gov/pubmed/22790873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.88
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