Integrative Structural Modelling of the Cardiac Thin Filament: Energetics at the Interface and Conservation Patterns Reveal a Spotlight on Period 2 of Tropomyosin

Cardiomyopathies are a major health problem, with inherited cardiomyopathies, many of which are caused by mutations in genes encoding sarcomeric proteins, constituting an ever-increasing fraction of cases. To begin to study the mechanisms by which these mutations cause disease, we have employed an i...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Margaret Sunitha, S, Mercer, John A., Spudich, James A., Sowdhamini, Ramanathan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Libertas Academica 2012
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468436/
https://ncbi.nlm.nih.gov/pubmed/23071391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BBI.S9798
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller