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Rho-kinase inhibition improves vasodilator responsiveness during hyperinsulinemia in the metabolic syndrome

In patients with the metabolic syndrome (MetS), the facilitatory effect of insulin on forearm vasodilator responsiveness to different stimuli is impaired. Whether the RhoA/Rho kinase (ROCK) pathway is involved in this abnormality is unknown. We tested the hypotheses that, in MetS patients, ROCK inhi...

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Detaylı Bibliyografya
Asıl Yazarlar: Schinzari, Francesca, Tesauro, Manfredi, Rovella, Valentina, Di Daniele, Nicola, Gentileschi, Paolo, Mores, Nadia, Campia, Umberto, Cardillo, Carmine
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468433/
https://ncbi.nlm.nih.gov/pubmed/22829585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00206.2012
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