Tumor Necrosis Factor-α Antagonism Improves Vasodilation During Hyperinsulinemia in Metabolic Syndrome

OBJECTIVE—Obesity is associated with chronic inflammation due to overproduction of proinflammatory cytokines, including tumor necrosis factor (TNF)-α. We assessed the effects of TNF-α neutralization by infliximab on vascular reactivity during hyperinsulinemia in obesity-related metabolic syndrome. R...

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Detalhes bibliográficos
Main Authors: Tesauro, Manfredi, Schinzari, Francesca, Rovella, Valentina, Melina, Domenico, Mores, Nadia, Barini, Angela, Mettimano, Marco, Lauro, Davide, Iantorno, Micaela, Quon, Michael J., Cardillo, Carmine
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2008
Assuntos:
Cardiovascular and Metabolic Risk
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453644/
https://ncbi.nlm.nih.gov/pubmed/18390795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc08-0219
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