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IL-13-induced changes in endogenous glucocorticoid metabolism in the lung regulate the proasthmatic response
Endogenous glucocorticoid (GC) activation is regulated by the intracellular GC-activating and -inactivating enzymes 11β-hydroxysteroid dehydrogenase (11β-HSD)1 and 11β-HSD2, respectively, that catalyze interconversion of inert cortisone and its bioactive metabolite cortisol. Because endogenous GCs a...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468426/ https://ncbi.nlm.nih.gov/pubmed/22773690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00125.2012 |
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