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Mechanism of glucocorticoid protection of airway smooth muscle from proasthmatic effects of long-acting β2-adrenoceptor agonist exposure

BACKGROUND: Chronic use of long-acting β(2)-adrenergic receptor (β2AR) agonists (LABAs), resulting in β2AR desensitization, has been associated with increased asthma morbidity. When LABAs are used in combination with inhaled glucocorticoids (GCs), however, asthma control is improved, raising the que...

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Detaylı Bibliyografya
Asıl Yazarlar: Nino, Gustavo, Hu, Aihua., Grunstein, Judith S., Grunstein, Michael M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866838/
https://ncbi.nlm.nih.gov/pubmed/20392484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2010.02.007
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