Mechanism regulating proasthmatic effects of prolonged homologous β(2)-adrenergic receptor desensitization in airway smooth muscle

Use of long-acting β(2)-adrenergic receptor (β2AR) agonists to treat asthma incurs an increased risk of asthma morbidity with impaired bronchodilation and heightened bronchoconstriction, reflecting the adverse effects of prolonged homologous β2AR desensitization on airway smooth muscle (ASM) functio...

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Main Authors: Nino, Gustavo, Hu, Aihua, Grunstein, Judith S., Grunstein, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770790/
https://ncbi.nlm.nih.gov/pubmed/19666775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00079.2009
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