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Mechanism regulating proasthmatic effects of prolonged homologous β(2)-adrenergic receptor desensitization in airway smooth muscle
Use of long-acting β(2)-adrenergic receptor (β2AR) agonists to treat asthma incurs an increased risk of asthma morbidity with impaired bronchodilation and heightened bronchoconstriction, reflecting the adverse effects of prolonged homologous β2AR desensitization on airway smooth muscle (ASM) functio...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770790/ https://ncbi.nlm.nih.gov/pubmed/19666775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00079.2009 |
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