Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines

BACKGROUND: Integrase defective lentiviral vectors (IDLV) represent a promising delivery system for immunization purposes. Human dendritic cells (DC) are the main cell types mediating the immune response and are readily transduced by IDLV, allowing effective triggering of in vitro expansion of antig...

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Bibliographic Details
Main Authors: Negri, Donatella RM, Rossi, Alessandra, Blasi, Maria, Michelini, Zuleika, Leone, Pasqualina, Chiantore, Maria Vincenza, Baroncelli, Silvia, Perretta, Gemma, Cimarelli, Andrea, Klotman, Mary E, Cara, Andrea
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468359/
https://ncbi.nlm.nih.gov/pubmed/22913641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-69
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