Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines

BACKGROUND: Integrase defective lentiviral vectors (IDLV) represent a promising delivery system for immunization purposes. Human dendritic cells (DC) are the main cell types mediating the immune response and are readily transduced by IDLV, allowing effective triggering of in vitro expansion of antig...

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Detalhes bibliográficos
Main Authors: Negri, Donatella RM, Rossi, Alessandra, Blasi, Maria, Michelini, Zuleika, Leone, Pasqualina, Chiantore, Maria Vincenza, Baroncelli, Silvia, Perretta, Gemma, Cimarelli, Andrea, Klotman, Mary E, Cara, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468359/
https://ncbi.nlm.nih.gov/pubmed/22913641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-69
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