Development and use of SIV-based Integrase defective lentiviral vector for immunization

Integrase (IN) defective lentiviral vectors have a high safety profile and might prove useful as immunizing agents especially against HIV-1. However, IN defective SIV-based vectors must be developed in order to test their potential in the non human primate models (NHP) of AIDS. To this aim we tested...

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Huvudupphovsmän: Michelini, Zuleika, Negri, Donatella RM, Baroncelli, Silvia, Spada, Massimo, Leone, Pasqualina, Bona, Roberta, Klotman, Mary E., Cara, Andrea
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754741/
https://ncbi.nlm.nih.gov/pubmed/19523909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.05.070
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