Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice

CD8+ T cells are an essential component of an effective host immune response to tumors and viral infections. Genetic immunization is particularly suitable for inducing CTL responses, because the encoded proteins enter the MHC class I processing pathway through either transgene expression or cross-pr...

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Bibliographic Details
Main Authors: Negri, Donatella R. M., Michelini, Zuleika, Baroncelli, Silvia, Spada, Massimo, Vendetti, Silvia, Bona, Roberta, Leone, Pasqualina, Klotman, Mary E., Cara, Andrea
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873659/
https://ncbi.nlm.nih.gov/pubmed/20508727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/534501
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