Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice

CD8+ T cells are an essential component of an effective host immune response to tumors and viral infections. Genetic immunization is particularly suitable for inducing CTL responses, because the encoded proteins enter the MHC class I processing pathway through either transgene expression or cross-pr...

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Detalhes bibliográficos
Main Authors: Negri, Donatella R. M., Michelini, Zuleika, Baroncelli, Silvia, Spada, Massimo, Vendetti, Silvia, Bona, Roberta, Leone, Pasqualina, Klotman, Mary E., Cara, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873659/
https://ncbi.nlm.nih.gov/pubmed/20508727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/534501
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