Optimization of Mucosal Responses after Intramuscular Immunization with Integrase Defective Lentiviral Vector

Many infectious agents infiltrate the host at the mucosal surfaces and then spread systemically. This implies that an ideal vaccine should induce protective immune responses both at systemic and mucosal sites to counteract invasive mucosal pathogens. We evaluated the in vivo systemic and mucosal ant...

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Detalhes bibliográficos
Main Authors: Rossi, Alessandra, Michelini, Zuleika, Leone, Pasqualina, Borghi, Martina, Blasi, Maria, Bona, Roberta, Spada, Massimo, Grasso, Felicia, Gugliotta, Alessio, Klotman, Mary E., Cara, Andrea, Negri, Donatella
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161417/
https://ncbi.nlm.nih.gov/pubmed/25210766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107377
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