Optimization of Mucosal Responses after Intramuscular Immunization with Integrase Defective Lentiviral Vector

Many infectious agents infiltrate the host at the mucosal surfaces and then spread systemically. This implies that an ideal vaccine should induce protective immune responses both at systemic and mucosal sites to counteract invasive mucosal pathogens. We evaluated the in vivo systemic and mucosal ant...

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Bibliografiska uppgifter
Huvudupphovsmän: Rossi, Alessandra, Michelini, Zuleika, Leone, Pasqualina, Borghi, Martina, Blasi, Maria, Bona, Roberta, Spada, Massimo, Grasso, Felicia, Gugliotta, Alessio, Klotman, Mary E., Cara, Andrea, Negri, Donatella
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161417/
https://ncbi.nlm.nih.gov/pubmed/25210766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107377
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