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Small molecule TSHR: Agonists and antagonists
TSH activates the TSH receptor (TSHR) thereby stimulating the function of thyroid follicular cells (thyrocytes) leading to biosynthesis and secretion of thyroid hormones. Because TSHR is involved in several thyroid pathologies, there is a strong rationale for the design of small molecule “drug-like”...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3467701/ https://ncbi.nlm.nih.gov/pubmed/21511239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ando.2011.03.002 |
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