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Small molecule TSHR: Agonists and antagonists

TSH activates the TSH receptor (TSHR) thereby stimulating the function of thyroid follicular cells (thyrocytes) leading to biosynthesis and secretion of thyroid hormones. Because TSHR is involved in several thyroid pathologies, there is a strong rationale for the design of small molecule “drug-like”...

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Hlavní autoři: Neumann, S., Gershengorn, M.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467701/
https://ncbi.nlm.nih.gov/pubmed/21511239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ando.2011.03.002
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