Generation of a Novel, Cox2-Targeted, Interferon-Expressing, Conditionally-Replicative Adenovirus for Pancreatic Cancer Therapy

BACKGROUND: Oncolytic adenoviruses provide a promising alternative for cancer treatment. Recently, adjuvant α-interferon has shown significant survival benefits for pancreatic cancer, yet was impeded by systemic toxicity. To circumvent these problems adenovirus with high-level targeted IFNα expressi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Armstrong, Leonard, Arrington, Amanda, Han, Joohee, Gavrikova, Tatyana, Brown, Eric, Yamamoto, Masato, Vickers, Selwyn M., Davydova, Julia
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467355/
https://ncbi.nlm.nih.gov/pubmed/22748294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjsurg.2012.02.016
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki