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Lesion-specific DNA-binding and repair activities of human O(6)-alkylguanine DNA alkyltransferase
Binding experiments with alkyl-transfer-active and -inactive mutants of human O(6)-alkylguanine DNA alkyltransferase (AGT) show that it forms an O(6)-methylguanine (6mG)-specific complex on duplex DNA that is distinct from non-specific assemblies previously studied. Specific complexes with duplex DN...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3467069/ https://ncbi.nlm.nih.gov/pubmed/22810209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks674 |
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