The Structure of the ζζ Transmembrane Dimer Reveals Features Essential for Its Assembly with the T Cell Receptor

The T cell receptor (TCR) αβ heterodimer communicates ligand binding to the cell interior via noncovalently associated CD3γε, CD3δε, and ζζ dimers. While structures of extracellular components of the TCR-CD3 complex are known, the transmembrane (TM) domains that mediate assembly have eluded structur...

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Autores principales: Call, Matthew E., Schnell, Jason R., Xu, Chenqi, Lutz, Regina A., Chou, James J., Wucherpfennig, Kai W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466601/
https://ncbi.nlm.nih.gov/pubmed/17055436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.08.044
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