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The Structure of the ζζ Transmembrane Dimer Reveals Features Essential for Its Assembly with the T Cell Receptor
The T cell receptor (TCR) αβ heterodimer communicates ligand binding to the cell interior via noncovalently associated CD3γε, CD3δε, and ζζ dimers. While structures of extracellular components of the TCR-CD3 complex are known, the transmembrane (TM) domains that mediate assembly have eluded structur...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466601/ https://ncbi.nlm.nih.gov/pubmed/17055436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.08.044 |
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