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The activating NKG2D receptor assembles in the membrane with two signaling dimers into a hexameric structure

The activating NKG2D receptor plays a critical role in innate and adaptive immune responses by natural killer cells and subpopulations of T cells. The human receptor assembles with the DAP10 signaling dimer, and it is thought that one NKG2D homodimer pairs with a single DAP10 dimer by formation of t...

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Autors principals: Garrity, David, Call, Matthew E., Feng, Jianwen, Wucherpfennig, Kai W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140444/
https://ncbi.nlm.nih.gov/pubmed/15894612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502439102
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