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Stoichiometry of the T-cell receptor–CD3 complex and key intermediates assembled in the endoplasmic reticulum

The T-cell receptor (TCR)–CD3 complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. Models of different stoichiometry and valency have been proposed based on cellular experiments and these have important implications for the mechanis...

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Detalhes bibliográficos
Main Authors: Call, Matthew E, Pyrdol, Jason, Wucherpfennig, Kai W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC423287/
https://ncbi.nlm.nih.gov/pubmed/15152191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600245
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