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Stoichiometry of the T-cell receptor–CD3 complex and key intermediates assembled in the endoplasmic reticulum

The T-cell receptor (TCR)–CD3 complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. Models of different stoichiometry and valency have been proposed based on cellular experiments and these have important implications for the mechanis...

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Bibliographic Details
Main Authors: Call, Matthew E, Pyrdol, Jason, Wucherpfennig, Kai W
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC423287/
https://ncbi.nlm.nih.gov/pubmed/15152191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600245
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