Lithocholic acid extends longevity of chronologically aging yeast only if added at certain critical periods of their lifespan

Our studies revealed that LCA (lithocholic bile acid) extends yeast chronological lifespan if added to growth medium at the time of cell inoculation. We also demonstrated that longevity in chronologically aging yeast is programmed by the level of metabolic capacity and organelle organization that th...

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Autors principals: Burstein, Michelle T., Kyryakov, Pavlo, Beach, Adam, Richard, Vincent R., Koupaki, Olivia, Gomez-Perez, Alejandra, Leonov, Anna, Levy, Sean, Noohi, Forough, Titorenko, Vladimir I.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466555/
https://ncbi.nlm.nih.gov/pubmed/22894934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21754
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